MRC LHA & NSHD > Study members > Data collection > Neuroscience clinical sub-study

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Neuroscience clinical sub-study

brain.jpgThe neuroscience clinical sub-study (also called Insight 46) is a clinical sub-study with the specific aims to identify brain changes that accompany healthy ageing, and detect brain changes that might help predict who is at greater risk of development dementia.

This sub-study will involve 500 study members who have been randomly selected from everyone who attended a clinic visit between 2006 and 2011. They will be asked to attend two clinic visits in London, two years apart. During these visits, study members will be asked about their health, medications and any concerns they have about memory. They will also be asked to perform a neurological examination, a walking test and some tests of memory and thinking. Vision, hearing and smell will be assessed and blood and urine samples will be taken. At the end of the day, study members will be asked to undergo a brain scan.

We are working with neurologists from the National Hospital for Neurology and Neurosurgery, and Institute of Neurology at UCL.

All travel and accommodation costs will be reimbursed.

Letters of invitation for the first round of clinic visits will be sent out between June 2015 and June 2017.

If you have any queries regardingĀ the appointment, please contact the study team onĀ 020 3448 4773.

For more general enquiries, please contact NSHD directly on 0800 952 0249 or 0207 670 5705 or